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Percentage of CH12 cells that underwent CSR to IgA in individual experiments. CSR was measured by flow cytometry. Results for CH12 cells expressing scramble shRNA or two PTBP2 shRNAs (PTBP2-1, PTBP2-2) are shown. ND: not determined.
| Expt. | scramble (%CSR to IgA) | PTBP2-1 (% CSR to IgA) | PTBP2-2 (% CSR to IgA) |
|---|---|---|---|
| 1 | 29.6 | 7.6 | ND |
| 2 | 36.9 | ND | 13.3 |
| 3 | 29.3 | 5.9 | 9.6 |
| 4 | 16.7 | 5.5 | 5.5 |
| 5 | 24.8 | 5.4 | 9.0 |
| 6 | 28.1 | 5.0 | 9.3 |
