Table 7.

Odds ratios and 95% confidence intervals of developmental disorders associated with intraventricular hemorrhage and a white matter lesion, alone and together. The models are adjusted for gestational age, sex, and public insurance. Early ventriculomegaly is not considered but child had to have a LATE SCAN (scan 3) to be included. Odds ratios in bold type are statistically significant at p < 0.05. The referent group is children without intraventricular hemorrhage or a white matter lesion.

Outcome	IVH only	WML only	IVH + WML
Quadriplegia	1.2 (0.4, 3.8)	28 (12, 64)	19 (9.2, 39)
Diplegia	2.1 (0.8, 5.7)	5.6 (1.5, 21)	4.5 (1.5, 13)
Hemiplegia	0.7 (0.1, 6)	5.6 (0.6, 50)	15 (4.9, 46)
MDI < 55	1.4 (0.8, 2.6)	3.5 (1.6, 7.8)	3.3 (1.8, 5.9)
MDI 55-69	1.6 (0.9, 3.0)	2.8 (1.2, 6.6)	1.0 (0.4, 2.6)
PDI < 55	1.8 (0.99, 3.1)	7.5 (3.5, 16)	5.9 (3.3, 11)
PDI 55-69	1.5 (0.9, 2.7)	3.6 (1.5, 8.5)	1.1 (0.5, 2.7)
HC Z-score < -2	1.8 (0.9, 3.7)	2.6 (0.95, 7.2)	3.5 (1.7, 7.5)
HC Z-score ≥ -2, < -1	1.1 (0.6, 1.9)	2.0 (0.9, 4.5)	2.0 (1.04, 4.5)
Strabismus	1.0 (0.5, 1.8)	3.4 (1.7, 6.9)	2.0 (1.1, 3.6)
Visual field deficit	1.2 (0.5, 3.0)	3.5 (1.3, 9.7)	3.9 (1.8, 8.3)
Impaired fixation	2.4 (1.2, 4.9)	2.9 (1.05, 8.0)	4.3 (2.2, 8.5)
Hearing impairment	2.4 (0.6, 9.3)	6.7 (1.7, 27)	4.2 (1.2, 15)

Abbreviations: IVH – intraventricular hemorrhage; WML – white matter lesion; MDI – Mental Development Index; PDI – Psychomotor Development Index; HC – head circumference