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. Author manuscript; available in PMC: 2013 Jul 26.
Published in final edited form as: Bioorg Med Chem. 2010 Aug 14;18(19):7015–7021. doi: 10.1016/j.bmc.2010.08.018

Scheme 1.

Scheme 1

Reagents and conditions: (a) 2,2-dimethoxypropane, camphosulfonic acid, acetone, rt; (b) NaBH4, EtOH, rt; (c) MsCl, Et3N, CH2C12, rt; (d) Na2S, DMF, 80 °C; (e) 60% AcOH, rt; (f) Pb(OAc)4, EtOAc, 0 °C; (g) NaBH4, EtOH, 0 °C; (h) POCl3, CH3CN, rt.