HFS-induced LTP, but not TBS-induced LTP, in the CA1 hippocampus of 2-month-old mice is dependent upon p38.
A and B, hippocampal slices were preincubated with either vehicle (filled squares) or MAP kinase inhibitor U0126 (20 μm) (open squares). C, hippocampal slices were preincubated with vehicle (closed squares), p38 MAP kinase inhibitors SB203580 (10 μm) (open squares), or BIRB0796 (10 μm) (open diamonds) and tested for HFS LTP (A and C) or TBS LTP (B and D), n > 6. Data represent the mean ± S.E.