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Binding of FVIII to LDLR fragments. In SPR, the LDLR fragments, LDLR exodomain (A), LDLR cluster (B), and CR doublets (C–H), were immobilized and tested for binding with various concentrations of FVIII (0, 56.3, 112.5, 225, and 450 nm). RU, resonance units.
