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. 2013 Jun 10;288(30):22033–22041. doi: 10.1074/jbc.M113.468108

FIGURE 9.

FIGURE 9.

Proposed interaction of LDLR with FVIII. The model is based on atomic coordinates of crystal structures of the LDLR exodomain (Protein Data Bank (PDB) ID 1N7D) and FVIII (PDB ID 2R7E). For the LDLR part, only the CR.2-5 region is shown (magenta and gray). In each CR domain, the coordinated Ca2+ is depicted as a sphere. The model was constructed using PyMOL.