FIGURE 5.

Interaction between the flexible loop and the next protomer related by the crystallographic symmetry. A, two homodimeric structures of holo-pro-form related by the crystallographic symmetry. Colored loops are loop 1 (Lys⁸²–Lys85, red), loop 2 (Ser²¹³–Phe²²³, yellow), and loop 3 (Ser⁵¹⁶–Gly⁵³², green) of holo-pro-form chain A. B, magnified view on the contacting region indicated by dotted rectangle. Dotted lines and small dashed line indicate the closet contacts between atoms, and the long dashed line indicates residues not visible in the electron density.