Table 1.
Baseline subject characteristics
| Healthy controls | Asthmatics | p value | |
|---|---|---|---|
| Sample size of qPCR data |
19 |
24 |
|
| Age, years |
34 ± 9 |
33 ± 12 |
0.71 |
| BMI |
26 ± 4 |
28 ± 5 |
0.20 |
| Gender (% F) |
42 |
50 |
0.84 |
| Ethnicity* |
|
|
|
| White |
10 |
10 |
|
| African-American |
1 |
2 |
|
| Hispanic |
3 |
6 |
|
| Asian/Pacific Islander |
4 |
5 |
|
| Native American |
1 |
1 |
|
| FEV1, % predicted |
99 ± 13 |
84 ± 13 |
0.0008 |
| Δ FEV1 with albuterol (% of baseline) |
5.0 ± .4.5 |
14.4 ± 9.5 |
0.0001 |
| FEV1/FVC |
0.78 ± 0.066 |
0.73 ± 0.074 |
0.02 |
| Methacholine PC20 (mg/ml) |
> 10 (n = 18) |
0.57 (0.07-4.40) |
<0.0001 |
| IgE, IU/ml |
20 (4–357), (n = 18) |
232 (2–6556) |
<0.0001 |
| Blood eosinophils, ×109/L |
0.11 (0.04-0.30) |
0.33 (0.05-0.75) |
<0.0001 |
| FeNO | 16 (9–49) | 62 (9–144), (n = 18) | 0.0004 |
Values reported as mean ± standard deviation, or median (range). All data are from the baseline visit except spirometry, which are reported from visit 2 (immediately before initiation of ICS). p- values are based on t-test or chi-square test for proportions unless otherwise noted.
* In cases of multiple ethnicities, the lowest-numbered ethnicity from this list is reported: 1. Hispanic, 2. Black, 3. Pacific Islander, 4. Native American, 5. Asian, 6. White.