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. Author manuscript; available in PMC: 2014 Sep 1.
Published in final edited form as: J Surg Res. 2013 Apr 5;184(1):290–298. doi: 10.1016/j.jss.2013.03.049

Figure 5. Histology Images of Lung Samples.

Figure 5

Figure 5

a. Representative lung sample from a mouse implanted with BxPC-3 RFP P0, small microscopic metastatic lesions are noted.

  1. Bright-field image of lung section from a mouse implanted with BxPC-3 RFP P0.
  2. Fluorescence image of lung section from a mouse implanted with BxPC-3 RFP P0.
  3. Enlarged fluorescence image of lung section from a mouse implanted with BxPC-3 RFP P0. Arrows indicate two small areas of metastatic foci within a section of lung tissue from a mouse harboring the BxPC-3 RFP parental line. Red fluorescence indicates the presence of tumor within the tissue sample.
  4. H&E image of lung section from a mouse implanted with BxPC-3 RFP P0.
  5. 4X magnification of H&E image of lung section from a mouse implanted with BxPC-3 RFP P0.
  6. 10X magnification of H&E image of lung section from a mouse implanted with BxPC-3 RFP P0.

b. Mice implanted with BxPC-3 RFP P6 had significantly more metastatic lesions to the lung than mice implanted with BxPC-3 RFP P0.

  1. Bright field image of lung section from a mouse implanted with BxPC-3 RFP P6.
  2. Fluorescence image of lung section from a mouse implanted with BxPC-3 RFP P6.
  3. Enlarged fluorescence image of lung section from a mouse implanted with BxPC-3 RFP P6. The red fluorescence indicates the presence of metastatic foci within the tissue sample. The area of fluorescence is significantly greater in the section of lung metastasis from a mouse harboring the BxPC-3 RFP P6 line.
  4. H&E image of lung section from a mouse implanted with BxPC-3 RFP P6.
  5. 4X magnification of H&E image of lung section from a mouse implanted with BxPC-3 RFP P6.
  6. 10X magnification of H&E image of lung section from a mouse implanted with BxPC-3 RFP P6.