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. Author manuscript; available in PMC: 2014 Oct 1.
Published in final edited form as: Nanomedicine. 2013 Feb 27;9(7):912–922. doi: 10.1016/j.nano.2013.02.006

Figure 6. PEGylation of cSCK alters mechanism of endocytosis.

Figure 6

Quantification of cSCK in MLE 12 cells by flow cytometry following pretreatment with endocytosis inhibitors. (A) Cells were pretreated with monodansylcadaverine (MDC, 200 μM), chlorpromazine (CPM, 100 μM), or dynasore (10 μM) for 30 min, then incubated with the indicated cSCK for 1 h. (B) The effect of combinations of endocytosis inhibitors on non-PEGylated cSCK uptake. Shown is the mean S.D. of six experiments with replicate samples. A significant difference in uptake compared to media is indicated (*, P < 0.05).