Table 1.

Baseline characteristics of 90 patients with stage IV non-small cell lung cancer and univariate significance in a Cox proportional hazards model for overall survival

Characteristic	n (%)	Mean (SD)	Comparison	Estimated HR	p
Sex			Male vs. female	1.43	0.114
Female	34 (38)
Male	56 (62)
Previous chemotherapy			Yes vs. no	0.96	0.850
No	66 (73)
Yes	24 (27)
Age		61.4 (9.2)	5-year increase	0.99	0.790
ECOG PS*			Poor vs. good	1.47	0.103
Good (0 or 1)	60 (67)
Poor (2 or 3)	30 (33)
SF-12** general health item			Fair, poor vs.	1.55	0.049
Fair or poor	42 (47)		excellent, very good,
Excellent, very good, or good	48 (53)		good
Mean MDASI interference		2.6 (2.3)	One-point increase	1.19	0.002
Mean MDASI symptom severity (five items)		2.4 (1.7)	One-point increase	1.11	0.138
SF-12 physical component summary		35.6 (11.4)	Five-point decrease	1.08	0.093
SF-12 mental component summary		47.4 (10.7)	Five-point decrease	1.01	0.824

^*Fifteen patients (17%) had ECOG PS = 0; 45 (50%) had ECOG PS = 1; 27 (30%) had ECOG PS = 2; three (3%) had ECOG PS = 3

^**Five patients (6%) responded excellent; 16 (18%), very good; 27 (30%), good; 33 (37%), fair; nine(10%), poor