Table 3. Associations of retinal vascular calibers with biochemical parameters.

			Retinal Arteriolar Caliber (microns)			Retinal Venular Caliber (microns)
	Risk Factors	Unit Change	β ± SE	Sβ	Pr > |t|	β ± SE	Sβ	Pr > |t|
Model 1 *	logeCRP	Per 0.1 log	0.14±0.09	0.04	0.14	0.58±0.12	0.13	0.0001
	Orosomucoid	Per 0.2 g/l	0.11±0.4	0.008	0.78	1.28±0.5	0.06	0.02
	SOD- 2	Per 0.3 UM	−0.86±0.5	−0.05	0.07	0.84±0.6	0.04	0.16
	GPx-3 Activity	Per 200 UM	1.33±0.4	0.09	0.0008	0.74±0.5	0.04	0.15
Model 2 †	logeCRP	Per 0.1 log	0.18±0.1	0.05	0.07	0.51±0.1	0.12	0.0001
	Orosomucoid	Per 0.2 g/l	0.10±0.4	0.007	0.85	1.26±0.4	0.06	0.01
	SOD- 2	Per 0.3 UM	−0.74±0.4	−0.04	0.09	0.70±0.7	0.05	0.22
	GPx-3 Activity	Per 200 UM	1.20±0.4	0.08	0.003	0.61±0.5	0.03	0.23
Model 3 §	logeCRP	Per 0.1 log	0.17±0.2	0.05	0.08	0.54±0.1	0.12	0.0001
	Orosomucoid	Per 0.2 g/l	0.10±0.4	0.007	0.85	1.34±0.6	0.07	0.01
	SOD- 2	Per 0.3 UM	−0.63±0.4	−0.03	0.12	0.59±0.8	0.04	0.35
	GPx-3 Activity	Per 200 UM	1.08±0.4	0.08	0.01	0.79±0.6	0.04	0.15

Abbreviations: logeCRP, logarithmic of high-sensitivity C-Reactive Protein; SOD- 2, superoxide dismutase 2; GPx-3, glutathione peroxidase activity; β, regression coefficient estimated by multivariate linear regression, SE β; standard error β; Sβ, standardized regression coefficient (computed by multiplying the original estimates by the sample standard deviation of the regressor and divising by the sample standard deviation of the retinal vascular caliber).

^* Model 1: gender-adjusted association of retinal vascular caliber.

^† Model 2: Multivariate association of retinal vascular caliber adjusted for age (years), gender (male vs. female), hypertension status (hypertensive vs. normotensive), current smoking status (current vs. never/past), body mass index (kg/m2), high-density-lipoprotein cholesterol (mmol/l), estimated glomerular filtration rate (Modification of the Diet in Renal Disease, ml/min/1.73 m2), and logarithmic of high-sensitivity C-Reactive Protein for SOD-2 and GPX-3, and GPX-3 for logeCRP and Orosomucoid.

^§ Model 3 : model 2 after exclusion of 138 diabetic subjects.