Table 6. Comparison of methods’ sensitivity for tests performed with the CLIP-Seq data.

Method	Features/Setup	Data set #1	Data set #2
RF	complete set	0.704	0.725
	top 12	0.774	0.756
SVM	complete set	0.464	0.549
	top 12	0.901	0.891
NB	complete set	0.591	0.657
	top 12	0.633	0.689
KNN	complete set	0.661	0.756
	top 12	0.675	0.633
J48	complete set	0.521	0.586
	top 12	0.732	0.743
GLM	complete set	0.000	0.027
	top 12	0.000	0.018
TargetSpy	seed	0.421	0.339
	no-seed	0.459	0.529

Data set #1 refers to interactions predicted by all softwares except miRanda (38 pairs).

Data set #2 comprises interactions predicted by all softwares, including miRanda (170 pairs).

Both TargetSpy tests were performed using the sensitivity as the threshold.