Skip to main content
. 2013 Jul 26;8(7):e68663. doi: 10.1371/journal.pone.0068663

Figure 2. Antibody response during the first few weeks after HLA antibody incompatible renal transplant in patients with an acute rise in donor specific HLA antibody.

Figure 2

This shows the changes in A) the donor kidney specific antibody (DSA) for HLA class I and II, B) third party class I and II, C) blood group antibodies and D) viral antibody levels in patients with significantly higher post-transplant peak DSA levels compared to pre-transplant levels over the first couple of months. Over a longer observation period there was no significant change in third party HLA antibody, IgG, IgM or IgA blood group antibody, cytomegalovirus (CMV) IgG, varicella zoster virus (VZV) IgG and Hepatitis B surface antigen (HBsAg) IgG antibody observed. Only patients with measurable viral antibody levels pre-transplant were included. Box plot shows the statistical significant changes in the groups €- p<0.05 pre-transplant vs. post-transplant; £ - p<0.05 post-transplant vs. late; $ - p<0.05 pre-transplant vs. late and ¥ - p<0.05 overall trend.