Figure 4. Patient with rise in third party HLA antibody after an HLA antibody incompatible renal transplant.

Exceptionally a change in third party HLA antibodies was not noted which was not explained by the current understanding of epitope sharing of the third party HLA with donor specific HLA. In this example donor-specific antibodies to HLA A30 and B60 were going down post transplant, but the third party antibody HLA A2 was increasing. Though the HLA A2 is known to share epitopes with HLA A30, the behaviour of these two antibodies was very different to each other. Also, the patient did not receive any blood products after the transplant.