Table 3. Multivariable odds ratios for association between individual patient risk factors and prescription of lipid lowering drugs.
| Multivariable models* | Patients (n = 365,718) | ||
| OR | 95% CI | P value | |
| Age group: | |||
| ≤44 | 1 | <0.001 | |
| 45–54 | 2.01 | 1.93–2.09 | |
| 55–64 | 3.59 | 3.45–3.73 | |
| ≥65 | 4.21 | 4.05–4.39 | |
| Gender (Men vs Women) | 1.46 | 1.42–1.49 | <0.001 |
| Smoking status** | 1.35 | 1.32–1.38 | <0.001 |
| Diabetes** | 4.49 | 4.35–4.64 | <0.001 |
| Family history of CHD** | 1.52 | 1.46–1.59 | <0.001 |
| Antihypertensive drugs use** | 1.46 | 1.43–1.50 | <0.001 |
| Deprivation (Townsend fifth): | |||
| 1 (least deprived) | 1 | <0.001 | |
| 2 | 1.03 | 1.00–1.06 | |
| 3 | 1.03 | 0.99–1.06 | |
| 4 | 1.09 | 1.05–1.12 | |
| 5 (most deprived) | 1.15 | 1.10–1.20 | |
| Total Cholesterol (mmol/L): | |||
| <5.0 | 1 | <0.001 | |
| 5.0–6.9 | 0.81 | 0.79–0.83 | |
| ≥7.0 | 2.20 | 2.12–2.29 | |
| HDL Cholesterol (mmol/L): | |||
| ≤1.2 | 1 | <0.001 | |
| 1.3–1.4 | 0.87 | 0.84–0.89 | |
| 1.5–1.7 | 0.74 | 0.72–0.76 | |
| ≥1.8 | 0.57 | 0.56–0.60 | |
| Systolic blood pressure (mm Hg): | |||
| <140 | 1 | <0.001 | |
| 140–159 | 1.09 | 1.07–1.12 | |
| ≥160 | 1.07 | 1.02–1.12 | |
| Diastolic blood pressure (mm Hg): | |||
| <90 | 1 | <0.001 | |
| 90–99 | 0.93 | 0.90–0.96 | |
| ≥100 | 0.85 | 0.79–0.91 | |
| Frequency of BP measurements: | |||
| 0 | 1 | <0.001 | |
| 1–3 | 2.61 | 2.51–2.70 | |
| ≥4 | 4.24 | 4.06–4.42 | |
Adjusted for clustering by practice.
*
Each risk factor is independently adjusted for other risk factors.
**
Referent is none or no disease.