Table 4. Multivariable odds ratios for association between individual risk factors and lipid lowering drugs in eligible and ineligible patients.

Multivariable model*	Eligible patients (n = 74,137)			Ineligible patients (n = 291,581)
	OR	95% CI	P value	OR	95% CI	P value
Age group:
≤44	1		<0.001	1		<0.001
45–54	1.58	1.48–1.70		2.51	2.38–2.65
55–64	1.98	1.86–2.12		5.28	5.00–5.57
≥65	1.75	1.63–1.88		7.41	7.00–7.84
Gender (Men vs Women)	1.13	1.08–1.18	<0.001	1.59	1.55–1.63	<0.001
Smoking status**	1.26	1.21–1.31	<0.001	1.42	1.38–1.45	<0.001
Diabetes**	3.43	3.27–3.59	<0.001	8.86	7.90–9.94	<0.001
Family history of CHD**	1.22	1.14–1.30	<0.001	1.70	1.61–1.80	<0.001
Antihypertensive drugs use**	1.26	1.21–1.31	<0.001	1.61	1.57–1.66	<0.001
Deprivation (Townsend fifth):
1 (least deprived)	1		<0.001	1		0.002
2	1.06	1.01–1.12		1.02	0.98–1.06
3	1.05	0.99–1.11		1.01	0.97–1.05
4	1.12	1.06–1.19		1.06	1.01–1.11
5 (most deprived)	1.19	1.11–1.27		1.10	1.04–1.16
Total Cholesterol (mmol/L):
<5.0	1		<0.001	1		<0.001
5.0–6.9	1.09	1.05–1.14		0.65	0.65–0.70
≥7.0	2.48	2.32–2.66		1.61	1.53–1.70
HDL Cholesterol (mmol/L):
≤1.2	1		<0.001	1		<0.001
1.3–1.4	0.99	0.95–1.04		0.91	0.87–0.94
1.5–1.7	0.93	0.88–0.98		0.77	0.74–0.81
≥1.8	0.85	0.79–0.92		0.61	0.58–0.64
Systolic blood pressure (mm Hg):
<140	1		0.05	1		<0.001
140–159	1.02	0.98–1.07		1.12	1.09–1.16
≥160	0.94	0.88–1.01		1.14	1.07–1.22
Diastolic blood pressure (mm Hg):
<90	1		0.002	1		<0.001
90–99	0.94	0.89–0.99		0.91	0.87–0.95
≥100	0.84	0.75–0.94		0.81	0.73–0.89
Frequency of BP measurements:
0	1		<0.001	1		<0.001
1–3	3.15	2.95–3.37		2.35	2.25–2.45
≥4	4.96	4.60–5.37		3.88	3.69–4.09

Adjusted for clustering by practice.

^* Each risk factor is independently adjusted for other risk factors.

^** Referent is none or no disease.