. 2013 Jul 26;8(7):e69457. doi: 10.1371/journal.pone.0069457

Table 2. Comparing populations of benign nuclei from negative biopsies in a case-control study: subsequent diagnosis of prostate cancer is associated with a “cancer-like” nuclear morphometric score^* (MFSp). Scores derived from external datasets.

	Model A^*		Model B^**
	AUC	95% CI	AUC	95% CI
Case-Control Biopsies: Subsequent PCa vs. No PCa (n = 40 subjects; 20 pairs)	0.68	0.51–0.84	0.71	0.54–0.87
	Paired t test P = 0.047		Paired t test P = 0.026

Model A: 5 features selected by backwards elimination (FeretY_ave, MaxDiameter_ave, Elongation_ave, Slope_ave and ODKurtosis_ave).

^**

Model B: 5 features (SumOD_sd, MaxDiam_sd, TSD_sd, TEntropy_sd, No.MedDensityObjects_sd), selected after competition among all models with ≤5 covariates based on leave-one-out AUC.

Table 2. Comparing populations of benign nuclei from negative biopsies in a case-control study: subsequent diagnosis of prostate cancer is associated with a “cancer-like” nuclear morphometric score* (MFSp). Scores derived from external datasets.

Table 2. Comparing populations of benign nuclei from negative biopsies in a case-control study: subsequent diagnosis of prostate cancer is associated with a “cancer-like” nuclear morphometric score^* (MFSp). Scores derived from external datasets.