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. 2013 Jul 26;8(7):e63429. doi: 10.1371/journal.pone.0063429

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© 2013 Patterson et al

This is an open-access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are properly credited.

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The scatter plots show CD8 and CD4 activation as a function of waking cortisol or diurnal cortisol slope. The slope presented in the graphs is the multivariate regression coefficient for T-cell activation as a function of cortisol measures, adjusted for age, viral load, and CD4 count. Figure 2A shows CD38 mean fluorescent intensity (MFI) on CD8+ T cell in relationship to waking cortisol. Figure 2B shows CD38 mean fluorescent intensity (MFI) on CD4+ T cell in relationship to waking cortisol. Figure 2C shows CD38 mean fluorescent intensity (MFI) on CD8+ T cell in relationship to diurnal cortisol slope. Figure 2D shows CD38 mean fluorescent intensity (MFI) on CD4+ T cell in relationship to diurnal cortisol slope. * = p<.05. ** = p≤.001.