Table 1. Baseline descriptive statistics.
Characteristic | Summary Statistic(s) |
Sample size (n) | 128 |
Age, median (10th–90th percentile) | 40 (29, 55) |
Male (%) | 96.9 |
Race/ethnicity (%) | |
White | 64.1 |
Black | 7.8 |
Latino | 16.4 |
Other | 11.7 |
CD4 (CD4+ cells/mm3): median (10th–90th percentile) | 469 (310, 786) |
HIV (log10 plasma HIV-1 RNA copies/mL): median (10th–90th percentile) | 4.3 (3.2, 4.9) |
T lymphocyte activation | |
CD4 T cell expression of CD38 (MFIa): median (10th–90th percentile) | 954 (583, 1419) |
CD8 T cell expression of CD38 (MFI): median (10th–90th percentile) | 1099 (764, 2181) |
HLA-DR+ CD38+ CD4+ T cell %b: median (10th–90th percentile) | 8 (4, 15) |
HLA-DR+ CD38+ CD8+ T cell %c: median (10th–90th percentile) | 40 (24, 57) |
Diurnal cortisol | |
Waking cortisol (nmol/L): median (10th–90th percentile) | 13 (6, 24) |
Waking +30 minute (nmol/L): median (10th–90th percentile) | 17 (9, 27) |
Cortisol awakening responsed (nmol/L): median (10th–90th percentile) | 3 (−5, 13) |
Bedtime cortisol (nmol/L): median (10th–90th percentile) | 3 (1, 14) |
Cortisol slopee (nmol/L): median (10th–90th percentile) | −10 (−19, −1) |
MFI, or mean fluorescence intensity, is a measure of the density of cell surface antigen.
Percent of CD4+ cells expressing HLA-DR and CD38 cell surface antigens.
Percent of CD8+ cells expressing HLA-DR and CD38 cell surface antigens.
Cortisol awakening response is the increase in cortisol from waking to 30 minutes post-waking.
Cortisol slope is the decline in cortisol over the course of the day, from waking to bedtime.