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. 2013 Jul 26;8(7):e69758. doi: 10.1371/journal.pone.0069758

Table 1. Measured Influx Values.

Metabolite Influx In vivo * (PV+HA) Perfusion**
Albumin (g/min/g liver) 0.02–0.05 0.00
Lactate (mmol/min/g liver) 0.03–0.1 0.00
Glucose (mg/min/g liver) 1.13–2.5 3.68
Alanine (umol/min/g liver) 0.36–0.92 1.86
Ammonia (umol/min/g liver) 0.11–0.2 0.00
Arginine (umol/min/g liver) 0–0.5 0.53
Asparagine (umol/min/g liver) 0.04–0.12 0.28
Aspartate (umol/min/g liver) 0.02–0.04 0.41
Cysteine (umol/min/g liver) 0.01–0.03 0.61
Glutamate (umol/min/g liver) 0.07–0.15 0.56
Glutamine (umol/min/g liver) 0.28–0.68 3.64
Glycine (umol/min/g liver) 0.26–0.6 1.23
Histidine (umol/min/g liver) 0.1–0.35 0.18
Isoleucine (umol/min/g liver) 0.07–0.23 0.70
Leucine (umol/min/g liver) 0.21–0.66 1.05
Lysine (umol/min/g liver) 0.18–0.54 1.10
Methionine (umol/min/g liver) 0.04–0.1 0.18
Ornithine (umol/min/g liver) 0.11–0.28 0.00
Phenylalanine (umol/min/g liver) 0.05–0.13 0.28
Proline (umol/min/g liver) 0.16–0.36 0.48
Serine (umol/min/g liver) 0.17–0.48 0.18
Threonine (umol/min/g liver) 0.19–0.47 0.62
Tyrosine (umol/min/g liver) 0.05–0.17 0.51
Valine (umol/min/g liver) 0.12–0.43 0.79
*

In vivo influx is the combined portal vein (PV) and hepatic artery (HA) contribution to that flux.

**

Perfusate influx is calculated according to the initial perfusate concentrations and a flow rate of 1.8 ml/min/g liver.