Table 1. Measured Influx Values.
Metabolite Influx | In vivo * (PV+HA) | Perfusion** |
Albumin (g/min/g liver) | 0.02–0.05 | 0.00 |
Lactate (mmol/min/g liver) | 0.03–0.1 | 0.00 |
Glucose (mg/min/g liver) | 1.13–2.5 | 3.68 |
Alanine (umol/min/g liver) | 0.36–0.92 | 1.86 |
Ammonia (umol/min/g liver) | 0.11–0.2 | 0.00 |
Arginine (umol/min/g liver) | 0–0.5 | 0.53 |
Asparagine (umol/min/g liver) | 0.04–0.12 | 0.28 |
Aspartate (umol/min/g liver) | 0.02–0.04 | 0.41 |
Cysteine (umol/min/g liver) | 0.01–0.03 | 0.61 |
Glutamate (umol/min/g liver) | 0.07–0.15 | 0.56 |
Glutamine (umol/min/g liver) | 0.28–0.68 | 3.64 |
Glycine (umol/min/g liver) | 0.26–0.6 | 1.23 |
Histidine (umol/min/g liver) | 0.1–0.35 | 0.18 |
Isoleucine (umol/min/g liver) | 0.07–0.23 | 0.70 |
Leucine (umol/min/g liver) | 0.21–0.66 | 1.05 |
Lysine (umol/min/g liver) | 0.18–0.54 | 1.10 |
Methionine (umol/min/g liver) | 0.04–0.1 | 0.18 |
Ornithine (umol/min/g liver) | 0.11–0.28 | 0.00 |
Phenylalanine (umol/min/g liver) | 0.05–0.13 | 0.28 |
Proline (umol/min/g liver) | 0.16–0.36 | 0.48 |
Serine (umol/min/g liver) | 0.17–0.48 | 0.18 |
Threonine (umol/min/g liver) | 0.19–0.47 | 0.62 |
Tyrosine (umol/min/g liver) | 0.05–0.17 | 0.51 |
Valine (umol/min/g liver) | 0.12–0.43 | 0.79 |
In vivo influx is the combined portal vein (PV) and hepatic artery (HA) contribution to that flux.
Perfusate influx is calculated according to the initial perfusate concentrations and a flow rate of 1.8 ml/min/g liver.