Figure 2. Change from screening to Day 14 in ENaC activity (average basal PD, Parts 1 and 2 combined).

Data are shown for the analysis of the average of both nostrils, the most-polarized nostril at screening carried forward, and the most-polarized nostril at each visit. Significant dose-dependent linear trends were demonstrated for the average of both nostrils and the most-polarized nostril at each visit (P<0.02).