Figure 1. Liver miR-122 and their target mRNA levels.
Rats were fed a STD (STD group) or a STD plus CD for 10 weeks. After 10 weeks, rats fed a STD plus CD were orally treated with 25 mg GSPE/kg bw (CD-GSPE group), 515 mg ω-3 PUFAs/kg bw (CD- DHA-OR), 25 mg GSPE and 515 mg ω-3 PUFAs/kg bw (CD-GSPE- DHA-OR group) or vehicle (CD control group) for 3 weeks simultaneously with the CD. Each value is the mean ± s.e.m. of seven rats. Letters denotes a significant difference between groups (p<0.05; One-way ANOVA).
