Fig. 1.

Longitudinal analysis of the human gut virome from a single individual. (A) Timeline of sample collection. Note that at some time points, two separate portions of the stool sample, taken approximately 1 cm apart, were processed and sequenced independently to assess reproducibility. (B) Rarefaction analysis of sampling depth by number of reads; detection of each contig is scored as positive if 50% of the contig is covered by sequence reads. (Inset) Contig recovery. The x-axis is the number of samples included (black line: 2 million reads; blue line: 15 million reads). (C) Contig spectrum, relating the lengths of the contigs assembled in bas pairs (x-axis) to the depth of coverage (y-axis). Circular contigs are shown as blue and linear contigs as red.