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. 2013 Jul 8;110(30):12379–12384. doi: 10.1073/pnas.1310604110

Fig. 6.

Fig. 6.

ZAP is not essential for the RIG-I–mediated type I IFN response. (A and B) Zc3hav1+/+ and Zc3hav1−/− MEFs were infected with MLV (2 × 1010 copies per μL) or VSV (MOI = 1) for 12 h. The levels of IFN-β (A) and Cxcl10 (B) proteins in the culture supernatants were measured with ELISAs. (C and D) Zc3hav1+/+ and Zc3hav1−/− bone marrow-derived dendritic cells were infected with NDV (2.5 × 105 pfu/mL) or IAV (PR8, 100 Hematoglutinin) for 24 h. The levels of IFN-β (C) and Cxcl10 (D) proteins in the culture supernatants were measured with ELISAs. The results shown are means ± SD (n = 3).