Skip to main content
. Author manuscript; available in PMC: 2013 Aug 15.
Published in final edited form as: Biol Psychiatry. 2012 Jul 27;74(4):250–256. doi: 10.1016/j.biopsych.2012.06.022

Table 2.

Diagnostic Test Statistics Considering the Validity of Early Antidepressant Response Predicting End of Study Response During Repeated Ketamine Infusions in Treatment-Resistant Major Depression

Hours Sensitivity Specificity PPV NPV
2 0.65 0.57 0.79 0.40
4 0.94 0.71 0.89 0.83
24 0.88 0.71 0.88 0.71

Table reports statistics of sensitivity, specificity, positive predictive value (PPV) and negative predictive value (NPV) considering response status at the 2h, 4h and 24h time points following the first dose of ketamine as a diagnostic test for predicting subsequent phase I response. See text for details.