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. Author manuscript; available in PMC: 2014 Aug 1.
Published in final edited form as: J Pediatr. 2013 Mar 7;163(2):383–387. doi: 10.1016/j.jpeds.2013.01.061

Figure.

Figure

Family pedigrees and genetic analyses. A, Consanguineous kindred with related nuclear families in Amish communities from Pennsylvania. B, Mennonite family from Arkansas. C, Amish-Mennonite family with children with PCD from several midwestern states, in which affected individuals had 2 heteroallelic DNAH5 mutations. Solid symbols indicate affected individuals; central dots, heterozygous individuals; dark-blue symbols, c.4348C>T (p.Q1450X) DNAH5 mutation; light-blue symbols, c.10815delT (p.P3606HfsX23) DNAH5 mutation; yellow symbols, DNAI1 (g.IVS1+2_3insT) mutation; red symbols, HEATR2 (p.L795P) mutation. Arrows specify the probands. Asterisks indicate subjects who underwent genetic testing. si, situs inversus totalis; sa, situs ambiguus