Table 4.
Echocardiographic EDV and ESV using a modified Simpson rule and a single-plane ellipsoid area-length formula applied to the parasternal long-axis view (see text for details). In contrast with the hemisphere-cylinder (HC) model (Tables 1 and 2), significant and marked underestimation of EDV is observed versus full-volume (FV) CMR.
EDV (μl) | ESV (μl) | |||||
---|---|---|---|---|---|---|
Echo- Simpson |
Echo-Area- Length |
CMR-FV | Echo- Simpson |
Echo-Area- Length |
CMR-FV | |
Diseased
n=18 |
511±130 *** |
538±140 ** |
669±111 | 199±104 ** |
217±118 * |
274±100 |
Normal and sham
n=9 |
397±71 ** |
418±75 * |
497±94 | 60±16 ** |
68±15 ** |
127±50 |
Overall
n=27 |
473±125 **** |
498±133 *** |
611±133 | 153±108 *** |
167±120 ** |
225±111 |
CMR, cardiac magnetic resonance imaging; Echo, echocardiography; EDV, end-diastolic volume; ESV, end-systolic volume; FV, full-volume and SD, standard deviation.
Values are expressed as mean ± SD. Only significant p-values for paired t-tests (vs. CMR-FV) are reported as follows:
p<0.05
p<0.01
p<0.001
p<0.0001