Table 3.
Sedation/Agitation at initiation and time of adverse effects (hypotension or bradycardia)
| Protocol (n = 25) | Historical control (n = 19) | |
|---|---|---|
| Initial sedation score a, n (%) | ||
| Agitated (RASS 4 to 1, Ramsay 1) | 9 (36) | 7 (37) |
| Calm (RASS 0, Ramsay 2) | 5 (25) | 6 (32) |
| Sedated (RASS −1 to −5, Ramsay 3 to 6) | 10 (40) | 4 (21) |
| Not documented | 1 (5) | 2 (10) |
| Sedation score at time of adverse drug reaction a, n (%) | ||
| Agitated (RASS 4 to 1, Ramsay 1) | 2 (8) | 4 (21) |
| Calm (RASS 0, Ramsay 2) | 0 | 4 (21) |
| Sedated (RASS −1 to −5, Ramsay 3 to 6) | 5 (20) | 4 (21) |
| Not documented | 0 | 1 (5) |