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. Author manuscript; available in PMC: 2013 Jul 28.
Published in final edited form as: Acta Neuropathol. 2012 Jun 30;124(4):517–529. doi: 10.1007/s00401-012-1002-8

Table 4.

Human prion disease types—terminology

No. Molecular types Histopathological types (Prion disease type with…..)
1 MM/MV 1 Diffuse synaptic deposits
2 VV2 Perineuronal and cerebellar plaque-like deposits
3 MV 2K Kuru plaques
4 MM 2C Cortical confluent vacuoles
5 MM 2T (=sFI) Thalamo-olivary atrophy
6 VV1 Corticostriatal synaptic deposits
7 MM 2V (=vCJD) Florid plaques
8 MM/MV 1+2C Mixed diffuse synaptic deposits and cortical confluent vacuoles
9 MV 2K+C Mixed Kuru plaques and cortical confluent vacuoles
10 Atypical