FIG. 6.

The pulmonary immune response after influenza A virus infection in sham and 15 Gy whole-lung irradiated CCSP^−/− mice. CCSP^−/− mice were infected with 120 HAU influenza A virus at 10 weeks post-irradiation. Panel A: Body weight changes over time. Changes in body weight were used as an indicator of morbidity after infection and are expressed as a percentage of body weight at the time of infection. (Two-way ANOVA with Fisher’s post-test, *P < 0.05 versus sham-infected, n = 30 for virus-infected groups, n = 7 for mock-infected groups.) Panel B: Kaplan-Meier survival curves presenting mean survival of each group throughout 21 days post-infection. Curves were analyzed using the log rank test. The difference in mortality between the sham-infected and irradiated-infected groups was not significant (P = 0.1547).