Table 3.

Meta-regression analysis of BDNF in anxiety disorders.

Study or subgroup	Anxiety			Control			Weight %	Std. mean difference IV, random, 95% CI	Std. mean difference IV, random, 95% CI
	Mean	SD	Total	Mean	SD	Total
Bonne et al., 2011	1	0.52	16	0.83	0.44	11	12.3	0.34 [−0.44, 1.11]
Dell'Osso et al., 2009	5300	1100	18	7400	1500	18	12.3	−1.56 [−2.32, −0.80]
dos Santos et al., 2011	0.47	0.038	25	0.75	0.06	25	10.4	−5.49 [−6.74, −4.24]
Hauck et al., 2010	0.49	0.21	34	0.25	0.14	34	13.1	1.33 [0.80, 1.86]
Maina et al., 2010	36,900	6420	24	41,590	7820	24	12.9	−0.64 [−1.23, −0.06]
Molendijk et al., 2011a	9310	3380	393	9490	3180	382	13.8	−0.05 [−0.20, 0.09]
Strohle et al., 2010	2700.2	4184.9	12	9700.45	7291.15	12	11.9	−1.14 [−2.01, −0.26]
Wang et al., 2011	1980	1590	74	4090	2000	32	13.3	−1.22 [−1.66, −0.77]
Total (95% Cl)			596			538	100.0	−0.94[−1.75, −0.12]

Heterogeneity: τ² = 1.26; χ² = 145.79, df = 7 (P < 0.00001); 1² = 95%.

Test for overall effect: Z = 2.25 (P = 0.02).