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Estimated sample size to detect a difference using a McNemar's Test of equality of paired proportions at a two-sided alpha ¼ 0.05 and power ¼ 90%; assuming 2.8% rate of hip fractures per year in the unprotected side and a 50% reduction in the protected side
| Adherence (%) | No. person years | No. events in unprotected side | No. events in protected side |
|---|---|---|---|
|
| |||
| 100 | 1088 | 30 | 15 |
| 50 | 1632 | 46 | 34.5 |
