. 2013 Jun 10;5(6):2144–2172. doi: 10.3390/nu5062144

Table 4.

Kinetic parameters showing effect of diet on glucose dynamics and insulin sensitivity, as assessed by the Simple model, for 60 min intervals for the 2 h during and 2 h after dextrose infusion in 14 volunteers after an overnight fast following the dietary interventions ¹.

Variable²	Time (min)	M	NSP	RS	WL	SED	P ³Time	P ³Diet	P ³ T × D
EGP	0–60	0.149	0.146	0.169	0.173	0.036	<0.001	0.601	0.966
	60–120	0.002	0.006	0.013	0.015
	120–180	0.076	0.083	0.101	0.128
	180–240	0.428	0.373	0.389	0.418
ILR	0–60	1.95 ^a	1.85 ^a,b	1.94 ^a	1.64 ^b	0.11	<0.001	0.830	0.012
	60–120	3.74 ^a	3.74 ^a	3.73 ^a	3.72 ^a
	120–180	3.07 ^a	3.23 ^a,b	3.20 ^a	3.42 ^b
	180–240	1.40 ^a	1.38 ^a	1.38 ^a	1.54 ^a
k₀₁	0–60	0.0124^a	0.0117^a	0.0122^a	0.0101^b	0.0011	<0.001	0.929	0.047
	60–120	0.0184^a	0.0182^a	0.0182^a	0.0172^a
	120–180	0.0261^a	0.0277^a	0.0268^a	0.0278^a
	180–240	0.0194^a	0.0203^a	0.0207^a	0.0219^b
ILR/Ins	0–60	8.83 ^a	9.33^a	8.67^a	13.50^a	2.834	<0.001	0.003	<0.001
	60–120	0.045^a	0.049^a	0.046^a	0.075^a
	120–180	9.17^a	9.34^a	9.84^a	17.84^b
	180–240	11.84^a	13.50^a	13.00^a	27.84^b

¹ Seven day maintenance (M), or 21 day high non-starch polysaccharide (NSP), high resistant starch (RS) or weight loss (WL) diets; ²EGP, endogenous glucose production (mmol/min); ILR, irreversible loss rate of glucose (mmol/min^-1); k₀₁, fractional rate of disappearance of glucose (/min); ILR/Ins, irreversible loss rate per unit insulin (μmol/L/pmol per min); ³p-values from ANOVA with volunteer and nested within volunteer, period, time and their interaction as random effects, and with diet, time and their interaction as fixed effects. When diet or the time by diet (T × D) interaction was significant post-hoc comparisons for diet were performed. SED values refer to main effects for diet. Values within rows with unlike superscripts are different at p < 0.05.