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. Author manuscript; available in PMC: 2013 Jul 29.
Published in final edited form as: J Pharmacol Exp Ther. 2007 Dec 17;324(3):1243–1254. doi: 10.1124/jpet.107.133074

Fig. 7.

Fig. 7

Proposed gross model and simulated drug activity. The feedback term (s + b)(s + c) associated with G(S) implies a two-compartment system with an associated degradation term. K(s) was found to be constant.