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. 2013 May 7;305(1):E89–E100. doi: 10.1152/ajpendo.00573.2012

Fig. 5.

Fig. 5.

Connecting the thyroid hormone receptor-β agonism of KB-2115 with decreased skeletal muscle glucose uptake (open bars, vehicle; filled bars, KB-2115). A: skeletal muscle tissue triglyceride content. B and C: assessment of skeletal muscle insulin signaling at the level of Akt phosphorylation (B) and AS-160 phosphorylation (C). D: skeletal muscle GLUT4 mRNA expression. E: skeletal muscle GLUT4 protein abundance measured by Western blot. F: skeletal muscle tether containing a UBX domain, for GLUT4 (TUG) protein abundance measured by Western blot (*P < 0.04 vs. vehicle). G: skeletal muscle sortilin 1 mRNA expression. H: skeletal muscle sortilin protein abundance measured by Western blot.