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. Author manuscript; available in PMC: 2013 Jul 29.
Published in final edited form as: Bioorg Med Chem Lett. 2011 Jan 14;21(5):1399–1401. doi: 10.1016/j.bmcl.2011.01.031

Table 1.

Anti-HIV activity and cytotoxicity of synthesized phlorogluconols.

Compound Cytotoxicity (µM) HIV-1 Infection (µM)
LC50 LC90 IC50 IC90
7 145 258 30.2 85
6 >100 N/D >100 >100
8 >100 N/D 39.8 85.6
9 >100 N/D 77.3 >100
10 >100 N/D 55.3 >100
11 >100 N/D 34.6 98.2
12 84.2 N/D 40.7 86.6