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. Author manuscript; available in PMC: 2013 Jul 29.
Published in final edited form as: Comp Med. 2005 Feb;55(1):12–23.

Table 2. Summary of the nonauditory effects of sound in laboratory animals.

System Results References
Cardiovascular ↑ blood pressure in cat, rat, rhesus monkey, and macaque monkev: ↑ heart rate in desert mule deer and rat 25, 87, 95,.145, 146, 197
↑ in vasoconstriction in rat; ↑ respiratory rates and adrenocorticotropin hormone in cat 15,110
no change in blood pressure in rat 16,109
Hormonal/biochemical ↑ norepinepherine, Cortisol, cholesterol, and plasma corticosterone in rat; 9, 42, 46, 77, 193
↑ noradrenergic and serotonergic activity in dorsal cochlear nucleus, posterior ventral cochlear nucleus, and serotonergic primary auditory cortex in rat;
↑ IgM and splenic natural killer cell levels and ↓ splenic lymphatic proliferation and peripheral phagocytic activity in rat
Reproductive ↓ in estrus in rat; ↓ fertility rates and ↑ weight of ovaries in both rats and rabbits 48, 60, 214
↑ suckling of voung in tree shrew; ↓ milk production in both dairy cattle and tree shrew 31, 50, 139
↑ in fetal mortality and resorption of pups in rat, rabbit, chicken, and pig 125, 159
Other accelerates expression of lupus in a mouse model 2
can cause audiogenic seizures 59, 96
↑ microvascular permeability and disruption of the intestinal lining in rat 97
↑ in tail flick latency (indication of ↑ analgesia) in rat 165
slower wound healing, ↓ in body weight, but no difference in food intake in rat 208
↓ body weight and ↑ in leukocytes and in adrenal gland and liver size in rat and rabbit 63, 134
Additional references 40, 45, 64, 68, 86, 91, 106, 133, 143, 160