Fig. 4.

The selective M₂-R antagonist methoctramine does not alter the carbachol inhibitory effects on the STBKC amplitude and frequency in freshly isolated rat DSM cells. A: representative recording of a freshly isolated DSM cell illustrating carbachol inhibitory effects on the amplitude and frequency of STBKCs in the presence of 1 μM methoctramine. B: summarized data illustrating the inhibitory effects of carbachol on the amplitude and frequency of STBKCs (n = 15, N = 15; *P < 0.05). Average amplitude and frequency of STBKCs in the presence of methoctramine were taken to be 100% (control), and data were normalized to controls.