Table 2.
Characteristics of Women Ages 15–53 Years at Index ECG (N = 410,782)
| Women with no | Women with | ||
|---|---|---|---|
| OC Prescription | OC Prescription | P‐Value | |
| Number | 376,106 | 34,676 | |
| Age, years (mean ± SD) | 40.7 ± 10.2 | 33.2 ± 9.6 | <0.0001 |
| Age categories, n (%) | <0.0001 | ||
| 15–20 | 23,841 (6.3) | 4,016 (11.6) | |
| 21–25 | 19,967 (5.3) | 54,84 (15.8) | |
| 26–30 | 27,669 (7.4) | 6,038 (17.4) | |
| 31 –35 | 37,228 (9.9) | 5,562 (16.0) | |
| 36–40 | 51,075 (13.6) | 4,926 (14.2) | |
| 41–45 | 71,144 (18.9) | 4,608 (13.3) | |
| 46–50 | 87,987 (23.4) | 3,346 (9.7) | |
| 51–53 | 38,409 (10.2) | 555 (1.6) | |
| Race, n (%) | <0.0001 | ||
| White | 154,193 (41.0) | 16,462 (47.5) | |
| Black | 35,516 (9.4) | 2,263 (6.5) | |
| Asian & Pacific Islander | 44,486 (11.8) | 3,100 (8.9) | |
| Latino | 55,911 (14.9) | 4,907 (14.2) | |
| Native American | 2,265 (0.6) | 152 (0.4) | |
| Mixed | 5,874 (1.6) | 456 (1.3) | |
| Missing | 77,861 (20.7) | 7,336 (21.2) | |
| Number of ECGs (mean ± SD) | 1.9 ± 2.1 | 1.6 ± 1.3 | <0.0001 |
| QTc at the index ECG, ms (mean ± SD) | 403.5 ± 22.6 | 400.8 ± 21.3 | <0.0001 |
| Number of follow‐up years (mean± SD) | 4.9 ± 3.6 | 4.5 ± 3.1 | <0.0001 |
| Smoking status, n (%) | <0.0001 | ||
| Never | 159,590 (42.4) | 17,232 (49.7) | |
| Former | 32,449 (8.6) | 2,989 (8.6) | |
| Current | 72,831 (19.4) | 5,257 (15.2) | |
| Missing | 111,236 (29.6) | 9,198 (26.5) | |
| Comorbidities, n (%) | |||
| Acute coronary syndrome | 2,915 (0.8) | 71 (0.2) | <0.0001 |
| Cardiac arrest | 261 (0.1) | 6 (0.02) | 0.0003 |
| Transient ischemic attack | 1790 (0.5) | 67 (0.2) | <0.0001 |
| Hemorrhagic stroke | 613 (0.2) | 18 (0.1) | <0.0001 |
| Ischemic stroke | 1782 (0.5) | 47 (0.1) | <0.0001 |
| Heart failure | 2,857 (0.8) | 84 (0.2) | <0.0001 |
| Ventricular dysrhythmias | 789 (0.2) | 52 (0.2) | 0.0184 |
| Obesity | 96,753 (25.7) | 7,536 (21.7) | <0.0001 |
| Hypertension | 76,789 (20.4) | 3,918 (11.3) | <0.0001 |
| Diabetes | 5,805 (1.5) | 142 (0.4) | <0.0001 |
| Hyperlipidemia | 35,045 (9.3) | 1,635 (4.7) | <0.0001 |
| End‐stage renal disease | 1,138 (0.3) | 30 (0.1) | <0.0001 |
ECG = electrocardiogram.