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H2O2 decreases ROMK current in a [K+]o-dependent manner. TPNQ-sensitive outward currents were measured in cells preincubated for >10 min with [K+]o = 1 or 10 mM with or without 0.1 mM H2O2. Data represent means ± SE for 4 experiments, with measurements in 2–3 cells for each condition. *P < 0.05, significant difference.
