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Apelin (10−6 M) treatment reduces PDGF-BB (10 nM)-stimulated connective tissue growth factor (CTGF) production in cultured human pancreatic stellate cells (PSCs). Top: Western blot of CTGF protein levels. Western blots represent results for 2 wells per treatment. Bottom: densitometric analysis of Western blots. Values are means ± SE; n = 6 wells per treatment. *P < 0.05 vs. control. †P < 0.05 vs. PDGF + vehicle.
