Table 2.

Pancreatic neutrophil densities 48 and 72 h after first cerulein injection

	48 h	72 h
WT + vehicle	5.0 ± 0.7	0.5 ± 0.2
WT + apelin	2.2 ± 0.3*	0.4 ± 0.1
APKO + vehicle	14.9 ± 1.0†	4.6 ± 1.4†
APKO + apelin	8.6 ± 1.3*†	1.7 ± 0.2*†

Values are means ± SE. Neutrophil density, number of neutrophils per unit area; WT, wild-type; APKO, apelin-knockout. Mice were subjected to 2 sequential acute pancreatitis (AP) episodes. Vehicle or apelin (50 μg per ip injection, twice per day (at 0800 and 1800)] was administered daily. Neutrophils were identified by GR1 immunostaining.

^*P < 0.05 vs. vehicle.

^†P < 0.05 vs. WT.