Fig. 6.

Bone mineral density in control and IL-10^−/− CD4⁺ T cell-transferred mice on the low or high vitamin D₃ diet. A: evaluation of cortical bone density by measurement of cortical area (Ct.Ar.), average cortical thickness (Ct.Th), and cortical area-to-total area ratio (Ct.Ar/Tt.Ar.). B: evaluation of trabecular bone density by quantitative assessment of bone volume fraction [ratio of bone volume to trabecular volume (BV/TV)], connectivity density (Conn.D), and trabecular number (Tb.N). Values are means ± SE; n = 5 and 7 for control and colitis groups, respectively. *P ≤ 0.05 vs. control (by ANOVA followed by Fisher's PLSD post hoc test).