Table 2.

Thiol scope of cross-coupling reactions on solid phase.

entry	thiol (R-SH)	product	4-SR-Phe product	total cross-coupled productsa
1		2	22%	99%
2		5	90%	90%
3		6	2%	2%
4	HS-(CH2)7-CH3		0%	0%
5		7	21 %b	45%b
6		2	57%b	67%b

^aIncludes disulfide products;

^bat 100 °C. R_N = Ac-Thr(tBu)- (solid) or Ac-Thr- (solution). R_C = -Pro-Asn(Trt)-NHRink (solid) or -Pro-Asn-NH₂ (solution).