Figure 5. Mast cell derived IL-6 promotes neutrophil clearance in LPS-induced lung injury.
Controls (WBB6), mast cell deficient (W/Wv) mice and W/Wv mice reconstituted with WT mast cells (W/Wv+WT) or IL-6−/− mast cells (W/Wv+IL-6−/−) were intratracheally challenged with 10μg LPS. At 24 hours post-treatment, (A) total and (B) differential cell counts were performed on BAL samples. n=5-7 mice per group from 3 independent experiments. Data is represented as mean ± SEM.