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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: Toxicol Appl Pharmacol. 2013 Jan 23;267(3):276–283. doi: 10.1016/j.taap.2013.01.005

Fig. 5.

Fig. 5

Immunohistochemistry of NTH1 and APE1 in the spleens of control rats (A and C) vs. aniline-treated rats (B and D). Control spleen showed sparse immunoreactivity for NTH1 and APE1, whereas spleen from aniline-treated rats showed increased immunoreactive cells and increased intensity of staining for NTH1 and APE1, confined to the red pulp areas. Also, APE1 showed much stronger immunoactivity compared to NTH1 following aniline insult with regard to both number of cells stained and overall staining intensity.