Fig. 2.

Expression profile of kdrl⁺ cells isolated from avascular mutant embryos. (A) Schematic diagram for molecular profiling. (B) Expression profile of known lineage specific markers in microarray (*q < 0.05). (C) Characteristics of genes which are up-regulated in endothelial cells in all three avascular mutant embryos. Total of 32 genes were shown to be up-regulated. (D) Expression profiles of putative transcription factors of which function have not previously implicated in the endothelial lineage. These genes were up in grc and clo (q = 0), but not down-regulated in cas.