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. 2013 Feb 21;35(2):166–172. doi: 10.1007/s10059-013-2307-8

Fig. 4.

Fig. 4.

Sox11b regulates sprouting angiogenesis during development. (A) Epifluorescent micrographs of control (top) or sox11b (bottom) morpholino (MO) injected embryos. Trunk regions posterior to the end of yolk extension are shown. Scale bar = 250 μm. (B) Intersegmental vessel and caudal vein defect in sox11b MO injected embryos at 34 hpf. Scale bar = 100 μm. (C) Truncation of ISVs and plexus defects at 48hpf. Scale bar = 250 μm. (D) Decreased venous sprouting angiogenesis in the caudal vein plexus (CVP) of sox11b MO injected embryos at 32hpf is quantified. (E) The effect of sox11b MO on the length of intersegmental vessels is quantified (N = 139, N = 10 embryos).